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Biointerfaces – AG Prof. A. Rosenhahn

Our research is driven by the desire to understand the interaction of microorganisms and cells with polymer materials to inspire the development of environmentally friendly antifouling and biomedical coatings. Surface modification and polymer synthesis in conjunction with advanced surface characterization is used to correlate surface properties with biological response for a knowledge driven development of new coating technologies. To gain a deeper insight into the structure and dynamics of surface colonization by microorganisms, we develop and apply microfluidic assays, 3D tracking techniques, and X-ray nanoanalysis.

NEWS:

28. Februar 2025

New Paper 2025

Discover how tuning the interfacial charge distribution of quasi-zwitterionic self-assembled monolayers impacts protein resistance and bacterial adhesion—and why surface dipole orientation plays a key role—in our latest publication.

Effect of Interfacial Charge Distribution in Mixed Charge-Equilibrated SAMs on the Attachment of Pathogens Karthäuser, J.; Ademmer, K.; Zimmermann, R.; Rosenhahn, A. ACS Applied Materials & Interfaces, 2025, 17(10), 16145-16155 https://doi.org/10.1021/acsami.4c20789
16. Februar 2025

New Paper 2025

Discover zwitterionic methacrylate-based hydrogels with photo-cross-linkable units that combine mechanical stability with high hydration — and how they resist protein adsorption and marine fouling, even in real-world sea tests, in our latest publication.

Enhanced Resistance of Zwitterionic Hydrogels against Marine Fouling Using a Zwitterionic Photo Cross-Linker Karthäuser, J.; Hansen, J.; Smajlji, A.; Hunsucker, K.; Yeshi, T.; Braga, C.; Patschorke, T.; Swain, G.; Rosenhahn, A.; Laschewsky, A. Langmuir, 2025, 41(7), 4545–4559 https://doi.org/10.1021/acs.langmuir.4c04351
10. Februar 2025

Welcome Luci

Our group is growing! Join us in welcoming our newest PhD student Luci as she kicks off her scientific adventures.


10. Januar 2025

Welcome Georg

Join us in welcoming our new doctoral researcher Georg as he begins his scientific journey with us.

2. Dezember 2024

New Paper 2024 1.12.24

Our HEMA thin film coatings, loaded with antifouling enzymes, are more than just protective — they’re a flexible testing platform for active agents, showing strong resistance to diatoms and algal spores alike. Find the article here:

Testing of Marine Fouling‐Inhibiting Enzymes in a Water‐Based Methacrylate Polymer Matrix. Gnanasampanthan, T.; Koschitzki, F.; Özcan, O.; Höppner, A.; Wanka, R.; Finlay, J. A.; Clare, A. S.; Rosenhahn, A.; Advanced Materials Interfaces, 2025, 12, 2400647 https://doi.org/10.1002/admi.202400647
10. November 2024

New Paper 2024

Explore how amphiphilic zwitterionic copolymer coatings swell in different salt environments—and how anions drive structural changes — using a multi-technique approach in our latest publication.

Antipolyelectrolyte Response of Amphiphilic Sulfobetaine Schardt, L.; Da Vela, S.; Guajardo, A. M.; Jaugstetter, M.; Tschulik, K.; Laschewsky, A.; Rosenhahn, A.; Rosenhahn, A. Advanced Materials Interfaces, 2024, 12, 2400610 https://doi.org/10.1002/admi.202400610
15. August 2024

Welcome Sabrina

Welcome our newest PhD student – Sabrina!
She’s diving into research, discovery, and plenty of coffee-fueled curiosity — we’re so excited to have her on board!


7. August 2024

Conference ICBZM

We are pleased to announce that Katrin and Jana recently attended the 5th International Conference on Bioinspired and Zwitterionic Materials at Cornell University in Ithaca, NY. We are proud to share that Jana was awarded third place in the young scholar poster competition.

We are looking forward to hosting the 6th ICBZM in Germany in 2026 together with Prof. Dr. Lienkamp (Saarland University)!


23. Juli 2024

New Paper

What happens when you blend superhydrophobic PFPE with hydrophilic zwitterions in one smart coating? Our new study reveals how composition controls antifouling performance in dynamic marine conditions. Check out our latest work on zwitterionic–PFPE coatings for the full story.

Marine Fouling Release Performance of Amphiphilic Carboxybetaine Perfluoropolyether Methacrylate Polymer Koschitzki, F.; Özcan, O.; Wanka, R.; Krisam, M.; Rosenhahn, A.; Rosenhahn, A. Advanced Materials Interfaces, 2024, 11, 2400370 https://doi.org/10.1002/admi.202400370
17. Juli 2024

New Paper 2024

We are thrilled to announce our latest publication, a collaboration between the Experimental Surgery department of Jochen Salber from the Ruhr University Bochum and other partners with our Analytical Chemistry – Biointerface department. This work explores the analysis of amphiphilic zwitterionic coatings for enhancing the performance of surgical implants.

In Vitro Biocompatibility Analysis of Protein-Resistant Amphiphilic Polysulfobetaines as Coatings for Surgical Implants in Contact with Complex Body Fluids Karthäuser, J. F.*; Gruhn, D.*; Martínez Guajardo, A.; Kopecz, R.; Babel, N.; Stervbo, U.; Laschewsky, A.; Viebahn, R.; Salber, J.; Rosenhahn, A. Frontiers in Bioengineering and Biotechnology, 2024, 12, 1–17 https://doi.org/10.3389/fbioe.2024.1403654
30. Juni 2024

Conference ICMCF

Axel and Leijla represented our group at the 20th International Congress on Marine Corrosion and Fouling in Guangzhou, China. A huge congratulations to Leijla, who took home 2nd place for her outstanding poster presentation!


2. Mai 2024

Congratulation Jana!

Jana has achieved a significant milestone by successfully defending her PhD thesis, which centered on zwitterionic hydrogels. We extend our heartfelt congratulations and best wishes for your future endeavors!  


29. April 2024

Welcome our new Postdoc Aleksandr!

We’re excited to welcome Aleksandr to our team as a new postdoctoral researcher! We’re eagerly anticipating his contributions to our work with microfluidics.
22. Januar 2024

New Paper 2024

Interested in delving deeper into how Joule heating enhances fouling inhibition in 3D printed superhydrophobic composite coatings? Dive into our latest paper for more insights!

Fouling Inhibition by Replenishable Plastrons on Microstructured, Superhydrophobic Carbon‐Silicone Composite Coatings Manderfeld, E.; Vogler, L.; Rosenhahn, A.. Advanced Materials Interfaces, 2024, 11, 10, 2300964

https://doi.org/10.1002/admi.202300964


4. Januar 2024

New Paper 2024

Explore methacrylate-based polymers containing sulfo- and sulfabetaines with varied spacer lengths and how the settlement of bacteria is affected in our latest publication. Spacer Effects in Sulfo‐ and Sulfabetaine Polymers on Their Resistance against Proteins and Pathogenic Bacteria Karthäuser, J. F.; Kopecz, R.; Schönemann, E.; Guajardo, A. M.; Laschewsky, A.; Rosenhahn, A.;. Advanced Materials Interfaces, 2024, 11, 5, 2300873

https://doi.org/10.1002/admi.202300873


14. November 2023

Congratulation Lisa!

Lisa successfully passed her PhD defense. Her work focused on the mobility, coordination and reaction in confinement of reverse micelles as well as polymerous hydrogels. We wish you all the best for the future!


11. September 2023

Scientific Group Retreat 2023

We recently organized our first-ever group retreat, thanks to the initiative of four of our PhD students: Lisa, Jana, Onur, and Regina. Over the course of five days in the picturesque Eifel region, we enjoyed a mix of informative presentations, engaging workshops, team-building exercises, and evenings filled with (friendly) Mario Kart races and lively table soccer tournaments.


1. September 2023

Welcome Katrin

Join us in welcoming Katrin, the newest member of our research group, as she embarks on her Ph.D. journey with us.


25. August 2023

Conference Lisa

Lisa recently participated in the 18th International Conference on Organized Molecular Films (ICOMF) in Frankfurt, where she was a awarded a poster price for her excellent presentation on the swelling processes of amphiphilic zwitterionic polymer coatings. Congratulations to Lisa on this well-deserved achievement!


1. August 2023

Climbing excursion

The whole group came together for a day of tree-climbing adventure, and even with the rainy weather, the outing was a great opportinuty for team bonding!